SIJ1777

SKU: orb2665478

Description

SIJ1777, a GNF-7 derivative, is a potent small molecule inhibitor for research on BRAF-mutant melanoma. It suppresses oncogenic signaling by inhibiting MEK/ERK and AKT activation, leading to apoptosis and the inhibition of cell migration, invasion, and colony growth in vitro.

Research Area

Cell Biology, Signal Transduction

Key Properties

• CAS Number: 839707-55-0
• MW: 536.51
• Purity: 99.96% (May vary between batches)
• Formula: C₂₆H₂₃F₃N₈O₂
• SMILES: O=C(NC1=CC=C(C(=C1)N2C(=O)N(C3=NC(=NC=C3C2)NC4=NN(C=C4)C)C)C)C5=CC=CC(=C5)C(F)(F)F
• Target: MEK,ERK,Akt,Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

59711891