SIC-19

SKU: orb2646361

Description

SIC-19, a SIK2 inhibitor, functions by promoting the degradation of SIK2 protein via the ubiquitination pathway. It inhibits the growth of cancer cells and sensitizes cells, ovarian cancer organoids, and xenograft models to PARP inhibitors (such as Olaparib).

Research Area

Signal Transduction

Key Properties

• CAS Number: 713112-69-7
• MW: 574.67
• Formula: C₂₉H₂₆N₄O₅S₂
• SMILES: O=C(NC(=S)NNC(=O)C1=C(SC(=C1C2=CC=C(OC)C(OC)=C2)C)NC(=O)C=3C=CC=CC3)C=4C=CC=CC4
• Target: SIK

Storage & Handling

• Storage: -20°C
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

SIK