Sibiromycin

SKU: orb1691851

Description

Sibiromycin is a natural glycosylated pyrrolobenzodiazepine (PBD) antitumor antibiotic. It functions by forming covalent adducts with guanine residues in the DNA minor groove. This mechanism supports its investigation in biochemical assays and as a lead compound for anticancer drug development in preclinical research.

Research Area

Infectious Disease & Virology, Molecular Biology

Key Properties

• CAS Number: 12684-33-2
• MW: 475.542
• Formula: C₂₄H₃₃N₃O₇
• SMILES: [H][C@@]12CC(\C=C\C)=CN1C(=O)c1cc(O[C@@H]3O[C@@H](C)[C@H](NC)[C@@](C)(O)[C@H]3O)c(C)c(O)c1N[C@@H]2O |c:6|
• Target: Others,DNA Alkylator/Crosslinker,Antibiotic

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

6437361