SIBA

SKU: orb1309101

Description

SIBA is a synthetic S-adenosylhomocysteine (SAH) analogue that acts as a broad inhibitor of S-adenosylmethionine-dependent transmethylation. It inhibits enzymes like SAH hydrolase and has demonstrated antiviral activity, reversibly blocking herpes simplex virus type 1 (HSV-1) replication in vitro.

Research Area

Cell Biology, Infectious Disease & Virology, Molecular Biology

Key Properties

• CAS Number: 35899-54-8
• MW: 339.41
• Purity: 99.48% (May vary between batches)
• Formula: C₁₄H₂₁N₅O₃S
• SMILES: CC(C)CSC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12
• Target: HSV,Nucleoside Antimetabolite/Analog,Parasite
• Solubility: DMSO:90 mg/mL (265.17 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (9.72 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

chick embryo fibroblasts, 5'-Isobutylthioadenosine, 5'-Deoxy-5'-isobutylthioadenosine, 3 LL, Analog, cancer, HSV, HSV-1, HEp2, Herpes simplex virus, malaria, NucleosideAntimetabolite, Nucleoside Antimetabolite, Nucleoside Antimetabolite/Analog, Parasite, inhibit, Inhibitor, SIBA, SAH, RMS-J1

Compound Identifiers

PubChem CID

123674