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SHR5428

SKU: orb2277819

Description

SHR5428 is a potent, selective, and orally bioavailable noncovalent CDK7 inhibitor with an enzymatic IC50 of 2.3 nM. It demonstrates robust cellular activity in triple-negative breast cancer models, such as MDA-MB-468 cells, with an IC50 of 6.6 nM. This inhibitor is a valuable chemical probe for researching transcriptional regulation and cell cycle progression in oncology.

Research Area

Cell Biology

Images & Validation

Key Properties

TargetCDK

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

Quality Guarantee

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Protocol Information