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SHP836

SKU: orb1706638

Description

SHP836 is a cell-permeable, allosteric inhibitor of the full-length SHP2 phosphatase with a reported IC50 of 12 µM. It serves as a valuable research tool for investigating SHP2 signaling in cancer and RASopathies, applicable in both cellular and biochemical assays.

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number1957276-35-5
MW352.26
FormulaC16H19Cl2N5
SMILESC[C@H]1CN(C[C@@H](C)N1)c1ncc(c(N)n1)-c1cccc(Cl)c1Cl
TargetPhosphatase,Others

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information