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SHP2-IN-9

SKU: orb1688335

Description

SHP2-IN-9 is a potent and selective SHP2 inhibitor (IC50 = 1.174 μM) with an 85-fold preference over SHP1 and enhanced blood-brain barrier penetration. It blocks SHP2-dependent signaling, inhibiting cancer cell proliferation in vitro and suppressing tumor growth in models of cervical cancer and glioblastoma in vivo.

Research Area

Metabolism Research, Signal Transduction

Images & Validation

Key Properties

MW385.46
FormulaC20H20FN3O2S
TargetPhosphatase,Others

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

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Protocol Information