SHP2-IN-34

SKU: orb2814062

Description

SHP2-IN-34 (Compound A8) is a phenylurea-based allosteric inhibitor of SHP2 phosphatase. It demonstrates potent anti-tumor activity, significantly inhibiting tumor growth in CT26 mouse colon carcinoma models, supporting its use in oncology research targeting the RAS/MAPK pathway.

Research Area

Metabolism Research, Signal Transduction

Key Properties

• CAS Number: 2924065-12-1
• MW: 518.46
• Formula: C₂₃H₂₅Cl₂N₇OS
• SMILES: O=C(NC=1C=CC=C(Cl)C1)NC=2C=CC=C(SC3=NC=C(N=C3N)N4CCC(N)(C)CC4)C2Cl
• Target: Phosphatase,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172677397