SHMT-IN-3

SKU: orb2814310

Description

SHMT-IN-3 (Hit 1) is a potent, non-competitive serine hydroxymethyltransferase (SHMT) inhibitor, demonstrating an IC50 of 0.53 µM against human SHMT1. This compound is a valuable chemical probe for investigating one-carbon metabolism in cancer research, applicable in both cellular and biochemical in vitro studies.

Key Properties

• CAS Number: 330638-43-2
• MW: 462.46
• Formula: C₂₄H₂₂N₄O₆
• SMILES: O=C(O)CCC(=O)NC=1C=CC(=CC1)C2=NC=CC(=N2)C=3C=CC(=CC3)NC(=O)CCC(=O)O
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

2712855