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ShK toxin TFA

SKU: orb3180577

Description

ShK toxin TFA (Stichodactyla helianthus neurotoxin TFA) is a neurotoxin that inhibits voltage-gated potassium channels (Kv1.3 channels). This toxin can be isolated from the crude extracts of the Caribbean sea anemone (Stichodactyla helianthus). It competes with Dendrotoxin I and α-dendrotoxin for binding to rat brain synaptosomal membranes, facilitating the release of acetylcholine. ShK toxin TFA suppresses K+ currents in cultured rat dorsal root ganglion neurons and also inhibits T lymphocyte proliferation.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

TargetPotassium Channel

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information

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