SHIP2-IN-1

SKU: orb1309102

Description

SHIP2-IN-1 is a potent and selective SHIP2 phosphatase inhibitor with an IC50 of 2 µM. It is a valuable research tool for studying SHIP2's role in insulin signaling and neuronal function, with applications in Alzheimer's disease research in both cellular and animal models.

Research Area

Metabolism Research, Signal Transduction

Key Properties

• CAS Number: 2252247-80-4
• MW: 379.22
• Purity: 99.16% (May vary between batches)
• Formula: C₁₇H₁₃Cl₂FN₄O
• SMILES: C[C@@H](Oc1cncc(c1)-c1cnc(N)nc1)c1c(Cl)ccc(F)c1Cl
• Target: Phosphatase
• Solubility: DMSO:90 mg/mL (237.33 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (8.7 mM)

Bioactivity

• Target IC50:
  SHIP2:2 µM
• In Vitro:
  PI(3,4)P2 production in HT22 cellssignificantly inhibited by SHIP2-IN-1 (10 μM) .

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, Inhibitor, Phosphatase, SHIP2 IN 1, SHIP2IN1, SHIP-2-IN-1, SHIP2-IN-1, SHIP2

Compound Identifiers

PubChem CID

138319691