(+)-SHIN1

SKU: orb1708534

Description

(+)-SHIN1 ((+)-RZ-2994) is the biologically active enantiomer of the SHMT1/2 inhibitor SHIN1. It potently inhibits human serine hydroxymethyltransferase isoforms 1 and 2, serving as a critical research tool for investigating one-carbon metabolism in cancer and other diseases in both cellular and animal models.

Key Properties

• CAS Number: 2443966-90-1
• MW: 400.47
• Formula: C₂₄H₂₄N₄O₂
• SMILES: CC(C)[C@]1(c2c(C)n[nH]c2OC(N)=C1C#N)c1cc(CO)cc(c1)-c1ccccc1
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

134335071