SH514

SKU: orb2945186

Description

SH514 is a specific IRF4 inhibitor (IC₅₀ = 2.63 µM) that binds the IRF4 DNA-binding domain, blocking its transcriptional activity and downregulating key oncogenic targets like MYC and Blimp1. It is a valuable chemical probe for studying multiple myeloma pathogenesis and treatment in both cellular and animal models.

Research Area

Immunology & Inflammation

Key Properties

• MW: 514.66
• Purity: 97.83% (May vary between batches)
• Formula: C₃₂H₃₈N₂O₄
• SMILES: C[C@@H]([C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2C(=O)C=C4[C@@]3(C=C(C(=O)C4(C)C)C#N)C)C)C(=O)NC5=CC=C(C=C5)OC
• Target: IFNAR,Others
• Solubility: 10% DMSO+90% Corn Oil:3.3 mg/mL (6.41 mM);DMSO:80 mg/mL (155.44 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

SH 514

Compound Identifiers

PubChem CID

172677105