SGK1-IN-6

SKU: orb2944808

Description

SGK1-IN-6 (compound 12f) is a potent small molecule inhibitor of SGK1, demonstrating an IC50 of 0.39 μM. It has shown efficacy in inhibiting tumor growth in PC3 cell xenograft models in mice without signs of toxicity, supporting its use in cancer research and kinase signaling studies.

Research Area

Cell Biology, Metabolism Research

Key Properties

• CAS Number: 3046378-98-4
• MW: 581.586
• Formula: C₃₀H₃₀F₃N₅O₄
• SMILES: O=C(NC1=CC=C(OC)C=C1)C2=CC=3C(=NC(=CC3C(F)(F)F)NC4=CC=C(C=C4OC)N5CCNCC5)C=C2OC
• Target: SGK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

173640858