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SGI-7079

SKU: orb1223373

Description

SGI-7079 is a potent and selective Axl inhibitor with potential anticancer activity. SGI-7079 effectively inhibited Axl activation in the presence of exogenous Gas6 ligand. SGI-7079 inhibited tumor growth in a dose dependent manner. Axl is a potential therapeutic target for overcoming EGFR inhibitor resistance.

Images & Validation

Key Properties

CAS Number1239875-86-5
MW455.53
Purity>98% (HPLC)
FormulaC26H26FN7
SMILESCN1CCN(CC1)c1ccc(Nc2nc3c(c(C)c[nH]3)c(n2)c2cc(CC#N)ccc2)cc1F
TargetCasein Kinase
SolubilityDMSO : ≥ 34 mg/mL. 74.64 mM

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

SGI-7079 | SGI 7079 | SGI7079

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  • SGI-7079 [orb1300290]

    98.70%

    1239875-86-5

    455.53

    C26H26FN7

    5 mg, 50 mg, 100 mg, 500 mg, 1 ml x 10 mM (in DMSO), 2 mg, 10 mg, 25 mg
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Protocol Information

SGI-7079 (orb1223373)

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Available Sizes

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200 mg
500 mg
2 mg
$ 100.00
5 mg
$ 140.00
10 mg
$ 200.00
25 mg
$ 400.00
50 mg
$ 560.00
100 mg
$ 740.00