SGC2085 HCl

• Catalog Number: orb1303308
• Category: Small Molecules
• Description: SGC2085 HCl
• CAS Number: 1821908-49-9
• Purity: 99.91%
• MW: 348.87
• SMILES: C(=O)([C@H](C)N)NCc1cc(c(cc1)Oc1cc(cc(c1)C)C)C.Cl
• Formula: C₁₉H₂₅ClN₂O₂
• Biological Activity: SGC2085 is a potent and selective coactivator associated arginine methyltransferase 1 (CARM1) Inhibitor with an IC50 of 50 nM and more than undred-fold selectivity over other PRMTs. CARM1 is an important positive modulator of Wnt/β-catenin transcription and neoplastic transformation in colorectal cancer as well as a critical factor in estrogen-stimulated breast cancer growth, and its depletion results in decreased proliferation of myeloid leukemia cells in vivo.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.