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SGC-NSP2hel-1

SKU: orb3135291

Description

SGC-NSP2hel-1 (RA-0188293) is a potent and selective oral inhibitor of the nsP2 helicase, with a CC50 greater than 250 µM and a selectivity index over 4000. It exhibits broad-spectrum activity against various alphaviruses. In preclinical small animal models of chikungunya virus (CHIKV) disease, SGC-NSP2hel-1 reduces viral replication and limits virus-induced pathology by forming a stable complex with nsP2 and ATP.

Research Area

Infectious Disease & Virology

Images & Validation

Key Properties

TargetVirus Protease

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information