SFTS virus Nucleocapsid Protein, His Tag

SKU: orb3158269

Description

The nucleocapsid (NP) protein of Severe Fever with Thrombocytopenia Syndrome virus (SFTSV) is encoded by the S segment of its tripartite RNA genome. NP plays a central role in viral replication by encapsidating the genomic RNA and forming ribonucleoprotein complexes with the polymerase. It is highly conserved among SFTSV strains and strongly immunogenic, making it a major target for diagnostic assays and serological studies. Because of its abundance and stability, recombinant NP is widely used as an antigen for ELISA, rapid tests, and antibody development against this emerging tick-borne phlebovirus.

Research Area

Infectious Disease & Virology

Images & Validation

• Application Notes:
  This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 28.8 kDa. The protein migrates as 33-37 kDa and 48-55 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Key Properties

• Expression System: HEK293
• Target: Nucleocapsid protein
• Reactivity: Virus
• Tag: N-10×His
• Expression Region: Ser 2 - Leu 245
• Endotoxins: 1.0 EU per μg
• Conjugation: Unconjugated
• MW: 28.8 kDa
• Purity: 90%

Storage & Handling

• Storage: -20°C
• Form/Appearance: Powder
• Buffer/Preservatives: PBS, 0.2 M Arginine, pH 7.4
• Expiration Date: 6 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Nucleocapsid protein

RefSeq:AJO16088.1