SF1126

SKU: orb1706641

Description

SF1126 is a first-in-class, pan and dual PI3K/BRD4 inhibitor developed as an RGDS-conjugated prodrug of LY294002. This design enhances solubility and promotes tumor-targeted delivery via integrin binding. It has demonstrated activity in both in vitro and in vivo cancer models, including studies in multiple myeloma and solid tumors.

Research Area

Cell Biology, Signal Transduction

Key Properties

• CAS Number: 936487-67-1
• MW: 852.84
• Formula: C₃₉H₄₈N₈O₁₄
• SMILES: C(OC(CCC(N[C@H](C(NCC(N[C@H](C(N[C@H](C(O)=O)CO)=O)CC([O-])=O)=O)=O)CCCNC(=N)N)=O)=O)[N+]1(CCOCC1)C=2OC3=C(C=CC=C3C(=O)C2)C4=CC=CC=C4
• Target: Others,PI3K,Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

92043140