Seselin

SKU: orb1297052

Description

Seselin is a natural coumarin isolated from Plumbago zeylanica, exhibiting documented anti-inflammatory and antiviral properties. It serves as a research tool for investigating these activities in both in vitro and in vivo experimental models.

Research Area

Immunology & Inflammation, Infectious Disease & Virology

Key Properties

• CAS Number: 523-59-1
• MW: 228.24
• Purity: >99.99% (May vary between batches)
• Formula: C₁₄H₁₂O₃
• SMILES: CC1(C)Oc2ccc3ccc(=O)oc3c2C=C1
• Target: Immunology/Inflammation related,Antiviral,Antifungal
• Solubility: DMSO:45 mg/mL (197.16 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (8.76 mM)

Bioactivity

• In Vivo:
  Seselin (3mg/kg, 10mg/kg, 30mg/kg, iv) ameliorated lung injury and decreased JAK2 phosphorylation level in lung tissue during mouse sepsis.
• In Vitro:
  Seselin (10uM) blocked signalling pathways that mediate the classical activation of macrophages in bone marrow‐derived macrophages.

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Antiviral, Immunology related, Immunologyrelated, inflammation, Inflammation related, Inflammationrelated, Seselin

Compound Identifiers

PubChem CID

68229