Sesaminol

SKU: orb2814216

Description

Sesaminol is an orally active Nrf2-ARE pathway activator that promotes Nrf2 nuclear translocation and upregulates antioxidant enzymes like NQO1. It demonstrates neuroprotective effects in cellular models, such as inhibiting 6-OHDA-induced ROS and apoptosis in SH-SY5Y cells, and in vivo against rotenone-induced Parkinson's pathology.

Research Area

Immunology & Inflammation, Metabolism Research, Signal Transduction

Key Properties

• CAS Number: 74061-79-3
• MW: 370.35
• Formula: C₂₀H₁₈O₇
• SMILES: OC1=C([C@@H]2[C@@]3([C@@]([C@H](OC3)C=4C=C5C(=CC4)OCO5)(CO2)[H])[H])C=C6C(=C1)OCO6
• Target: Nrf2,Reactive Oxygen Species

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

94672