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(-)-Sesamin

SKU: orb1984114

Description

(-)-Sesamin is a neuroprotective lignan studied for Parkinson's disease research. It demonstrates efficacy in models of 6-OHDA-induced neurotoxicity by modulating key signaling pathways, including activation of ERK1/2 and inhibition of p38/JNK-caspase-3 cascades, as shown in both in vitro and in vivo studies.

Research Area

Cell Biology, Protein Biochemistry, Signal Transduction

Images & Validation

Key Properties

CAS Number13079-95-3
MW354.35
Purity99.36% (May vary between batches)
FormulaC20H18O6
SMILES[C@@]12([C@]([C@@H](OC1)C=3C=C4C(=CC3)OCO4)(CO[C@H]2C=5C=C6C(=CC5)OCO6)[H])[H]
TargetCaspase,JNK,ERK,p38 MAPK
SolubilityDMSO:80 mg/mL (225.77 mM)

Storage & Handling

Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Sesamin, ( ) Sesamin, ()Sesamin

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Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

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Protocol Information

(-)-Sesamin (orb1984114)

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25 mg
$ 110.00
DispatchUsually dispatched within 5-10 working days
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