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SeSA-HCPT

SKU: orb3210618

Description

SeSA-HCPT is an orally active dual-target inhibitor with activity against both Topo I and HDAC. It induces significant DNA damage, apoptosis, and S-phase arrest in prostate cancer cells. Additionally, SeSA-HCPT can inhibit the proliferation and migration of cancer cells. It damages homologous recombination by inhibiting the KIF4A-RAD51 signaling pathway. Moreover, SeSA-HCPT significantly suppresses CRPC tumor growth with minimal systemic toxicity.

Images & Validation

Key Properties

TargetHDAC,Topoisomerase,Apoptosis,DNA/RNA Synthesis,Kinesin

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information