Seratrodast

SKU: orb1310830

Description

Seratrodast (ABT-001) is a selective thromboxane A2 receptor (TP) antagonist, first approved in Japan in 1997 for asthma therapy. It is widely used in respiratory disease research to investigate bronchoconstriction and inflammation mechanisms in both in vitro and in vivo experimental models.

Research Area

Cell Biology, Immunology & Inflammation, Metabolism Research, Molecular Biology, Neuroscience, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 112665-43-7
• MW: 354.44
• Purity: 99.69%
• Formula: C₂₂H₂₆O₄
• SMILES: C(CCCCCC(O)=O)(C1=C(C)C(=O)C(C)=C(C)C1=O)C2=CC=CC=C2
• Target: PPAR,JNK,MDM-2/p53,Reactive Oxygen Species,ROS,COX,Ferroptosis,Prostaglandin Receptor
• Solubility: DMSO:50 mg/mL (141.07 mM);10% DMSO+90% Saline:2.5 mg/mL (7.05 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Seratrodast, Prostaglandin Receptor, ProstaglandinReceptor, TXA2R, inhibit, Inhibitor, COX, AA 2414, AA2414, AA-2414, ABT001, ABT-001, ABT 001

Compound Identifiers

PubChem CID

2449