Sepin-1

SKU: orb1304902

Description

Sepin-1 is a non-competitive separase inhibitor (IC50 = 14.8 µM) that suppresses tumor growth in mouse xenograft models and inhibits proliferation while inducing apoptosis in human cancer cell lines, supporting its use in oncology research.

Key Properties

• CAS Number: 163126-81-6
• MW: 223.19
• Purity: 98.51%
• Formula: C₉H₉N₃O₄
• SMILES: CC1(C)[N+]([O-])=C2C=CC(=CC2=[N+]1[O-])[N+]([O-])=O
• Target: Others
• Solubility: DMSO:Slightly soluble

Bioactivity

• Target IC50:
  Separase:14.8 µM

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Sepin 1, Sepin1, Sepin-1, Separase, 2H-Benzimidazole, 2,2-dimethyl-5-nitro-, 1,3-dioxide

Compound Identifiers

PubChem CID

2736269