Senexin A hydrochloride

SKU: orb2283349

Description

Senexin A hydrochloride is a selective CDK8/19 inhibitor (IC50=280 nM for CDK8) that blocks p21-mediated transcription, NF-κB-dependent promoter activity, and CMV-driven expression. It is a valuable chemical probe for studying transcription, inflammation, and cancer biology in cellular models.

Research Area

Cell Biology

Key Properties

• CAS Number: 1780390-76-2
• MW: 310.78
• Formula: C₁₇H₁₅ClN₄
• SMILES: N(CCC1=CC=CC=C1)C=2C3=C(C=CC(C#N)=C3)N=CN2.Cl
• Target: CDK,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

90488980