Senaparib

SKU: orb1297996

Description

Senaparib (IMP4297) is an orally bioavailable, highly selective PARP1/2 inhibitor demonstrating potent antitumor activity. It is a research tool for investigating DNA damage response pathways in cancers such as ovarian and breast, with studies showing efficacy in both cellular and animal models.

Research Area

Epigenetics & Chromatin, Molecular Biology

Key Properties

• CAS Number: 1401682-78-7
• MW: 478.45
• Purity: 99.80%
• Formula: C₂₄H₂₀F₂N₆O₃
• SMILES: Fc1ccc(Cn2c3cccc(F)c3c(=O)[nH]c2=O)cc1C(=O)N1CCN(CC1)c1ncccn1
• Target: PARP
• Solubility: 10% DMSO+90% Corn Oil:3.3 mg/mL (6.9 mM);DMSO:75 mg/mL (156.76 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

cancer, breast, inhibit, IMP 4297, IMP4297, IMP-4297, pancreatic, poly ADP ribose polymerase, PARP1, PARP, PCa, PARP2, Inhibitor, Senaparib

Compound Identifiers

PubChem CID

68389008