Semapimod tetrahydrochloride

SKU: orb1694480

Description

Semapimod tetrahydrochloride

Research Area

Cell Biology, Immunology & Inflammation, Signal Transduction

Key Properties

• CAS Number: 164301-51-3
• MW: 890.74
• Purity: 99.80% (May vary between batches)
• Formula: C₃₄H₅₆Cl₄N₁₈O₂
• SMILES: Cl.Cl.Cl.Cl.C\C(=N/NC(N)=N)c1cc(NC(=O)CCCCCCCCC(=O)Nc2cc(cc(c2)C(\C)=N\NC(N)=N)C(\C)=N\NC(N)=N)cc(c1)C(\C)=N\NC(N)=N
• Target: TLR,Interleukin,MAPK,TNF,p38 MAPK
• Solubility: DMSO:1 mg/mL (1.12 mM);H2O:1 mg/mL (1.12 mM)

Bioactivity

• In Vivo:
  In male OZ rats, Semapimod tetrahydrochloride (5 mg/kg; i.p.; once daily for 2 weeks) restored endothelium-dependent vasorelaxation.

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

MAPK, CPSI-2364 tetrahydrochloride, Semapimod, TLR4, TLR6

Compound Identifiers

PubChem CID

9554199