Semapimod tetrahydrochloride

• Catalog Number: orb1694480
• Category: Small Molecules
• Description: Semapimod tetrahydrochloride
• Purity: 99.80%
• MW: 890.74
• Biological Activity: Semapimod tetrahydrochloride (CPSI-2364 tetrahydrochloride) is a synthetic ornithine mitogen-activated protein kinase blocker and pro-inflammatory cytokine production inhibitor that interferes with macrophage and microglia function. Sematimod tetrahydrochloride inhibits TLR4 signaling, TNF-α, IL-1β, and IL-6, and is used in the study of Crohn's disease and other inflammatory conditions.
• CAS Number: 164301-51-3
• Formula: C₃₄H₅₆Cl₄N₁₈O₂
• SMILES: Cl.Cl.Cl.Cl.C\C(=N/NC(N)=N)c1cc(NC(=O)CCCCCCCCC(=O)Nc2cc(cc(c2)C(\C)=N\NC(N)=N)C(\C)=N\NC(N)=N)cc(c1)C(\C)=N\NC(N)=N
• Storage: -20°C
• Note: For research use only