Semaglutide TFA

SKU: orb1708552

Description

Semaglutide TFA is a GLP-1 receptor agonist used in research for type 2 diabetes and obesity. It promotes weight loss, improves glycemic control, and reduces cardiovascular risk, with transient GI effects as common side effects. This analog is applicable in both in vitro binding assays and in vivo metabolic disease models.

Research Area

Pharmacology & Drug Discovery

Key Properties

• Target: Glucagon Receptor
• Molecular Weight: 4225.6482
• Purity: 99.94% (May vary between batches)
• Formula: C₁₈₉H₂₉₀F₃N₄₅O₆₁
• SMILES: CC[C@@H]([C@@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(NCC(O)=O)=O)CCCNC(N)=N)=O)=O)CCCNC(N)=N)=O)C(C)C)=O)CC(C)C)=O)Cc(cn1)c2c1cccc2)=O)C)=O)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](C(C)C)NC([C@@H](NC([C@@H](NC([C@H]([C@H](O)C)NC([C@@H](NC([C@H]([C@H](O)C)NC(CNC([C@@H](NC(C(C)(NC([C@H](Cc3ncnc3)N)=O)C)=O)CCC(O)=O)=O)=O)=O)Cc4ccccc4)=O)=O)CO)=O)CC(O)=O)=O)=O)CO)=O)CO)=O)Cc5ccc(O)cc5)=O)CC(C)C)=O)CCC(O)=O)=O)=O)CCC(N)=O)=O)C)=O)C)=O)CCCCNC(COCCOCCNC(COCCOCCNC(CC[C@H](C(O)=O)NC(CCCCCCCCCCCCCCCCC(O)=O)=O)=O)=O)=O)=O)CCC(O)=O)=O)Cc6ccccc6)=O)C.OC(C(F)(F)F)=O

Storage & Handling

• Storage: store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

910463-68-2, 910463-68-2 free base, GLP-1 receptor, GlucagonReceptor, Glucagon Receptor, Semaglutide TFA, Semaglutide TFA (910463 68 2 free base), Semaglutide TFA (910463682 free base), Semaglutide TFA (910463-68-2 free base)

Quick Database Links

Gene Symbol

Glucagon Receptor