Cart summary

You have no items in your shopping cart.

Semagacestat

SKU: orb1225074

Description

A potent γ-secretase inhibitor that inhibits β-amyloid Aβ42, Aβ38 and Aβ40 with IC50 of 10.9, 12 and 12.1 nM, respectively.

Images & Validation

Key Properties

CAS Number425386-60-3
MW361.4
Purity>98% (HPLC)
FormulaC19H27N3O4
TargetNotch|γsecretase(Aβ38)|γsecretase(Aβ40)|γsecretase(Aβ42)

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
DisclaimerFor research use only

Similar Products

  • Semagacestat [orb1301052]

    97.10%

    425386-60-3

    361.44

    C19H27N3O4

    1 ml x 10 mM (in DMSO), 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 2 mg
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Documents Download

Datasheet
Product Information
Download

Request a Document

Protocol Information

Semagacestat (orb1225074)

  • Star
  • Star
  • Star
  • Star
  • Star
  • 0.0
Based on 0 reviews

Participating in our Biorbyt product reviews program enables you to support fellow scientists by sharing your firsthand experience with our products.

Login to Submit a Review

No reviews yet

Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

(This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

200 mg
500 mg
2 mg
$ 80.00
5 mg
$ 100.00
10 mg
$ 170.00
25 mg
$ 290.00
50 mg
$ 500.00
100 mg
$ 730.00