Selatinib

SKU: orb1695236

Description

Selatinib is an orally bioavailable, potent dual inhibitor of EGFR and ErbB2 (HER2). It demonstrates anticancer activity by inhibiting the proliferation of NCI-N87 gastric cancer cells in vitro and has shown efficacy in xenograft tumor models in vivo.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• CAS Number: 1275595-86-2
• MW: 565.06
• Purity: 98.00% (May vary between batches)
• Formula: C₂₉H₂₆ClFN₄O₃S
• SMILES: CS(=O)CCNCc1ccc(o1)-c1ccc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2c1
• Target: EGFR

Bioactivity

• Target IC50:
  EGFR:13 nM|ErbB2:22.5 nM

Storage & Handling

• Storage: store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

ErbB2, EGFR, Selatinib

Compound Identifiers

PubChem CID

51348455