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sEH-IN-23

SKU: orb3211445

Description

sEH-IN-23 is a soluble epoxide hydrolase inhibitor with an IC50 of 0.8 nM for human sources and 0.7 nM for murine sources. It inhibits the production of inflammatory factors mediated by NF-κB activation, reactive oxygen species (ROS) generation, and the release of pro-inflammatory cytokines IL-1β, IL-6, and TNF-α. Exhibiting anti-inflammatory activity in acute lung injury models, sEH-IN-23 can be utilized for research into acute lung injury.

Images & Validation

Key Properties

TargetNF-κB,Interleukin,Epoxide Hydrolase,ROS

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information