β-Secretase Inhibitor II

SKU: orb1690722

Description

β-Secretase Inhibitor II is a tripeptide aldehyde compound that potently inhibits β-secretase (BACE1), with reported IC50 values of 700 nM against total Aβ and 2.5 µM against Aβ 1-42. It is widely used in Alzheimer's disease research for in vitro enzymatic assays and cellular models of amyloid pathology.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 263563-09-3
• MW: 461.59
• Formula: C₂₅H₃₉N₃O₅
• SMILES: CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C)C=O
• Target: Beta-Secretase,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

10253763