SDH-IN-36

SKU: orb3173751

Description

SDH-IN-36 (Compound 17) is an α-D-tocopherol derivative that functions by inhibiting SDHC and blocking electron transport, leading to increased ROS and the induction of apoptosis. SDH-IN-36 effectively suppresses the proliferation of various tumor cells, including SSK4 (GI50= 0.156 µM), SSNU638 (GI50= 0.659 µM), and SKATOIII (GI50= 0.490 µM). This compound significantly inhibits tumor growth and can be utilized in cancer research, such as studies on gastric cancer.

Research Area

Cell Biology, Immunology & Inflammation, Metabolism Research

Key Properties

• CAS Number: 261929-60-6
• MW: 487.77
• Formula: C₃₁H₅₃NO₃
• SMILES: CC1=C2C(=C(C)C(OCC(N)=O)=C1C)CC[C@](CCC[C@@H](CCC[C@@H](CCCC(C)C)C)C)(C)O2
• Target: Apoptosis,Mitochondrial Metabolism,ROS

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Apoptosis,Mitochondrial Metabolism,ROS