SD 0006

SKU: orb1299956

Description

SD-0006 (SD-06) is a potent and selective p38α MAPK inhibitor with an IC50 of 110 nM. It is widely used in research to investigate inflammatory pathways and has demonstrated efficacy in cellular models and animal studies of rheumatoid arthritis.

Research Area

Cell Biology, Signal Transduction

Key Properties

• CAS Number: 271576-80-8
• MW: 397.86
• Purity: 98.32% (May vary between batches)
• Formula: C₂₀H₂₀ClN₅O₂
• SMILES: OCC(=O)N1CCC(CC1)c1n[nH]c(c1-c1ccncn1)-c1ccc(Cl)cc1
• Target: p38 MAPK,Autophagy
• Solubility: DMSO:29 mg/mL (72.89 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.03 mM)

Bioactivity

• Target IC50:
  p38 MAPK:110 nM (IC50)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

SD0006, SD-0006, SD06, SD-06, SD 0006, SD 06, p38MAPK, p38 MAPK, Inhibitor, inhibit, Autophagy

Compound Identifiers

PubChem CID

9865587