Scoulerine HCl

SKU: orb3179979

Description

Scoulerine HCl is a multi-target inhibitor with antibacterial, antitumor, and antioxidant activities. Scoulerine HCl targets GABA receptors and BACE1 and inhibits mitochondrial dehydrogenase activity, thereby suppressing cancer cell proliferation, migration, invasion, epithelial-mesenchymal transition, and stemness maintenance. Scoulerine HCl also disrupts microtubule structure by acting on the PI3K/Akt/mTOR signaling axis and α1D-adrenergic receptors, thereby inducing cell cycle arrest and apoptosis. Additionally, Scoulerine HCl regulates endoplasmic reticulum stress and mitochondrial function, and possesses various pharmacological activities, including anti-Plasmodium falciparum and antiemetic and antitussive effects.

Key Properties

• CAS Number: 51486-68-1
• MW: 363.84
• Purity: 98.62% (May vary between batches)
• Formula: C₁₉H₂₂ClNO₄
• SMILES: OC=1C=C2[C@]3(N(CC=4C(C3)=CC=C(OC)C4O)CCC2=CC1OC)[H].Cl
• Target: PI3K,Akt,GABA Receptor,Beta-Secretase,Adrenergic Receptor,Apoptosis

Storage & Handling

• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

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Gene Symbol

PI3K,Akt,GABA Receptor,Beta-Secretase,Adrenergic Receptor,Apoptosis