Scoulerine HCl

SKU: orb3179979

Description

Scoulerine HCl is a multi-target inhibitor with antibacterial, antitumor, and antioxidant activities. Scoulerine HCl targets GABA receptors and BACE1 and inhibits mitochondrial dehydrogenase activity, thereby suppressing cancer cell proliferation, migration, invasion, epithelial-mesenchymal transition, and stemness maintenance. Scoulerine HCl also disrupts microtubule structure by acting on the PI3K/Akt/mTOR signaling axis and α1D-adrenergic receptors, thereby inducing cell cycle arrest and apoptosis. Additionally, Scoulerine HCl regulates endoplasmic reticulum stress and mitochondrial function, and possesses various pharmacological activities, including anti-Plasmodium falciparum and antiemetic and antitussive effects.

Research Area

Cell Biology, Neuroscience, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 51486-68-1
• MW: 363.84
• Purity: 99.99% (May vary between batches)
• Formula: C₁₉H₂₂ClNO₄
• SMILES: OC=1C=C2[C@]3(N(CC=4C(C3)=CC=C(OC)C4O)CCC2=CC1OC)[H].Cl
• Target: Apoptosis,PI3K,Akt,Adrenergic Receptor,GABA Receptor,Beta-Secretase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Apoptosis,PI3K,Akt,Adrenergic Receptor,GABA Receptor,Beta-Secretase