SCH 221510

SKU: orb1704079

Description

SCH 221510 is a potent and selective orally bioavailable NOP receptor agonist (Ki=0.3 nM, EC50=12 nM). It exhibits anxiolytic-like effects in preclinical models and is a valuable research tool for investigating the N/OFQ-NOP receptor system in neurological disorders, including anxiety and depression.

Research Area

Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 322473-89-2
• MW: 397.55
• Purity: 99.74% (May vary between batches)
• Formula: C₂₈H₃₁NO
• SMILES: C(N1[C@@]2(C[C@@](O)(C[C@]1(CC2)[H])C3=CC=CC=C3)[H])(C4=C(C)C=CC=C4)C5=C(C)C=CC=C5
• Target: Opioid Receptor
• Solubility: DMSO:50 mg/mL (125.77 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.03 mM)

Bioactivity

• Target IC50:
  NOP:12 nM( EC50)|NOP:0.3 nM(Ki )

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Opioid Receptor, OpioidReceptor, NOP receptor, SCH221510, SCH-221510, SCH 221510

Compound Identifiers

PubChem CID

24879901