SC144 hydrochloride

SKU: orb1909045

Description

SC144 hydrochloride is a first-in-class, orally bioavailable small molecule inhibitor targeting gp130 (IL6ST). It blocks ligand-induced gp130 signaling, STAT3 activation, and downstream gene expression, effectively inducing apoptosis in human ovarian cancer cells in vitro. Its research applications extend to studying oncogenic signaling and therapeutic potential in various cancers.

Research Area

Cell Biology, Immunology & Inflammation

Key Properties

• CAS Number: 917497-70-2
• MW: 358.76
• Formula: C₁₆H₁₂ClFN₆O
• SMILES: Cl.O=C(NNC1=NC=2C=C(F)C=CC2N3C=CC=C13)C4=NC=CN=C4
• Target: Interleukin,Others,Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

66921431