SC-III3

SKU: orb1695249

Description

SC-III3, a novel scopoletin derivative, induces non-apoptotic, non-necrotic cell death in HepG2 hepatoma cells via mitochondrial-mediated AMPK/mTOR pathway-dependent autophagy. It demonstrates both in vitro cytotoxicity and in vivo efficacy by suppressing tumor growth in HepG2 xenograft models, supporting its use as a research tool for autophagy and cancer biology studies.

Key Properties

• CAS Number: 1660110-65-5
• MW: 371.77
• Formula: C₁₉H₁₄ClNO₅
• SMILES: N(C(/C=C/C1=CC=C(Cl)C=C1)=O)C2=CC=3C(OC2=O)=CC(O)=C(OC)C3
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

118731107