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SC-2001

SKU: orb1699377

Description

SC-2001 is a small molecule MCL-1 inhibitor that induces apoptosis in breast cancer cells by blocking STAT3 phosphorylation via SHP-1 upregulation. It also overcomes STAT3-mediated sorafenib resistance in hepatocellular carcinoma through RFX-1/SHP-1 activation, as demonstrated in in vitro studies.

Research Area

Cell Biology, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number1383727-17-0
MW368.23
FormulaC18H14BrN3O
SMILESC(C=1NC(C2=CC=3C(N2)=CC=C(Br)C3)=CC1OC)=C4C=CC=N4
TargetBcl-2 Family,Apoptosis,STAT,Others

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

Protocol Information