SBP-3264

SKU: orb1297744

Description

SBP-3264 is a novel, small molecule inhibitor targeting the serine/threonine kinases STK3 and STK4 (MST1/2). It is a valuable research tool for studying the Hippo signaling pathway in both cellular and animal models, particularly in contexts of cell proliferation, apoptosis, and immune regulation.

Key Properties

• CAS Number: 2869148-13-8
• MW: 369.85
• Purity: 99.59% (May vary between batches)
• Formula: C₁₉H₂₀ClN₅O
• SMILES: CC(=O)NC1CCN(CC1)c1ncnc2[nH]cc(-c3cccc(Cl)c3)c12
• Target: Others
• Solubility: DMSO:1 mg/mL (2.7 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.7 mM)

Bioactivity

• In Vivo:
  SBP-3264 possessed favorable pharmacokinetic and pharmacodynamic properties in mice.
• In Vitro:
  SBP-3264 specifically inhibited the Hippo signaling pathway in cultured mammalian cells.

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

SBP3264, SBP-3264, SBP 3264

Compound Identifiers

PubChem CID

162366980