SBI-581

SKU: orb1688373

Description

SBI-581 is a potent and selective oral TAO3 kinase inhibitor (IC50=42 nM). It blocks invadopodia formation by promoting TKS5α accumulation on RAB11 vesicles and shows significant in vivo antitumor activity with reasonable pharmacokinetics in mouse models, supporting cancer metastasis research.

Research Area

Protein Biochemistry

Key Properties

• MW: 383.44
• Formula: C₂₄H₂₁N₃O₂
• SMILES: OC1(C#CC2=CC=CC(NC/3=O)=C2C3=C\C4=CC5=C(C=CC=C5)N4)CCNCC1
• Target: Serine Protease

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Serine Protease