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SBC-115076

SKU: orb1223114

Description

SBC-115076 is a potent extracellular proprotein convertase subtilisin kexin type 9 (PCSK9) antagonist.

Images & Validation

Key Properties

CAS Number489415-96-5
MW527.61
Purity>98% (HPLC)
FormulaC31H33N3O5
SMILESCc1cc(C(=O)C2=C(O)C(=O)N(C2c2ccncc2)CCCN2CCOCC2)ccc1OCc1ccccc1
TargetSrc
SolubilityDMSO : ≥ 32 mg/mL; 60.65 mM

Bioactivity

In Vivo
Animal model: Female Wistar rats (high-fat diet (HFD)-fed). Dosage: 4 mg/kg. Administration: S. c. ; daily for 3 weeks. Result: Superior to atorvastatin in instigating weight loss, cholesterol reduction, and attenuation of mitochondrial oxidative stress in oxidative muscle fibers of obese female rats.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

SBC-115076 | SBC 115076 | SBC115076.

Similar Products

  • SBC-115076 [orb1305249]

    99.89% (May vary between batches)

    489415-96-5

    527.61

    C31H33N3O5

    2 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 500 mg, 1 ml x 10 mM (in DMSO), 1 mg
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Protocol Information

Available Sizes

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2 mg
$ 90.00
5 mg
$ 140.00
10 mg
$ 180.00
25 mg
$ 310.00
50 mg
$ 540.00
100 mg
$ 830.00
500 mg
$ 1,820.00