SBC-110736

SKU: orb1223257

Description

SBC-110736 is a novel inhibitor of proprotein convertase subtilisin kexin type 9 (PCSK9), and has been shown to lower cholesterol levels in mice.

Key Properties

• CAS Number: 1629166-02-4
• MW: 413.51
• Purity: >98% (HPLC)
• Formula: C₂₆H₂₇N₃O₂
• SMILES: O=C(c1ccc(NC(C)=O)cc1)N3CCN(CC3c2ccccc2)c4ccc(C)cc4
• Target: GluR
• Solubility: DMSO : ≥ 100 mg/mL. 241.83 mM

Bioactivity

• In Vivo:
  SBC-110736 (male C57BL/6 mice) lowers cholesterol levels in mice that were fed high fat diet, showing a mean of 38% reduction in total cholesterol levels after two weeks relative to high fat diet animal levels and a mean 50% reduction toward return to regular diet cholesterol levels.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

SBC-110736 | SBC 110736 | SBC110736

Quick Database Links

Gene Symbol

GluR