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SB-747651A

SKU: orb1699379

Description

SB-747651A is a potent and selective ATP-competitive inhibitor of MSK1 (IC50 = 11 nM) that targets its N-terminal kinase domain. This compound also inhibits related kinases including MSK2, PKA, PKB, RSK, and p70S6K in cellular assays, making it a valuable tool for studying kinase signaling pathways in inflammation, cancer, and neurological research.

Research Area

Signal Transduction

Images & Validation

Key Properties

CAS Number607372-46-3
MW342.4
FormulaC16H22N8O
SMILESC(C)N1C=2C(N=C1C=3C(N)=NON3)=CN=CC2CNC4CCNCC4
Targetp38 MAPK,Others

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

Protocol Information