SB-583355

SKU: orb3135493

Description

SB-583355 (Compound 56) is a potent G2A antagonist. It is synthesized through a Suzuki reaction of 4-methoxyphenylboronic acid with 3-bromo-4-hydroxybenzoic acid under specific conditions, followed by amide coupling. SB-583355 effectively blocks G2A activation mediated by 9-HOPE or T-10148 in CHO-K1 cells expressing human G2A. This compound is useful for investigating inflammation, myeloid leukemia, and neuropathic pain.

Key Properties

• CAS Number: 3040121-49-8
• MW: 472.58
• Formula: C₂₉H₃₂N₂O₄
• SMILES: OC=1C(=CC(C(N[C@@H](CC2=CC=CC=C2)C(NC3CCCCC3)=O)=O)=CC1)C4=CC=C(OC)C=C4
• Target: GPCR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

GPCR