SB 271046 hydrochloride

• Catalog Number: orb1303142
• Category: Small Molecules
• Description: SB 271046 hydrochloride
• CAS Number: 209481-24-3
• Purity: 98%
• MW: 488.45
• SMILES: Cl.C[C@@H](CN1CC(=O)NC(=O)C1)N1CC(=O)NC(=O)C1
• Formula: C₂₀H₂₂ClN₃O₃S₂·HCl
• Biological Activity: SB 271046 hydrochloride is selective, orally active 5-HT6 antagonist (pKi values are 9.02-8.92, 6.35, 6.55, 6.27 at 5-HT6, 5-HT1A, 5-HT1D and D3, and 6.05, 5.95, 5.76, 5.73, 5.62, 5.55, 5.41, 5.39, 5.27 and 200-fold selective over 55 other receptors, enzymes and ion channels. It increases extracellular aspartate and glutamate in the frontal cortex and exhibits anticonvulsant activity (EC50: 0.16 μM).
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.