SB-1295

SKU: orb2278064

Description

SB-1295 is a potent oral CDK9/T1 inhibitor (IC50: 0.17 µM) with antiproliferative activity against cancer cell lines like HCT 116 and MIA PaCa-2. It induces apoptosis in MIA PaCa-2 cells via ROS elevation and mitochondrial dysfunction, supporting its use in oncology research for studying cell cycle and cell death mechanisms.

Research Area

Cell Biology, Immunology & Inflammation, Metabolism Research, Signal Transduction

Key Properties

• MW: 443.88
• Formula: C₂₃H₂₂ClNO₆
• Target: Apoptosis,CDK,Reactive Oxygen Species

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Apoptosis,CDK,Reactive Oxygen Species