SARS-CoV-2 Mpro-IN-50

SKU: orb3173538

Description

SARS-CoV-2 Mpro-IN-50 (Compound 30) is a non-covalent inhibitor of SARS-CoV-2 Mpro with an IC50 of 14 nM. This compound also serves as a pan-coronavirus Mpro inhibitor, showing IC50 values ranging from 20 to 190 nM against SARS-CoV-1 Mpro, 229E Mpro, HKU1 Mpro, MERS Mpro, NL63 Mpro, and OC43 Mpro. It exhibits significant antiviral activity against the SARS-CoV-2 omicron variant (EC50: 22 nM). SARS-CoV-2 Mpro-IN-50 is useful for coronavirus infection research.

Key Properties

• CAS Number: 3038701-72-0
• MW: 552.51
• Formula: C₂₅H₂₅F₅N₆O₃
• SMILES: N(C([C@H](NC(C(F)(F)F)=O)[C@@H](C)C)=O)[C@H]1[C@@H](CCN(C(=O)C=2C=3N(C=NC3)C=CN2)C1)C4=CC(F)=CC(F)=C4
• Target: SARS-CoV

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

SARS-CoV