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Catalog Number | orb1744898 |
---|---|
Category | Small Molecules |
Description | SARS-CoV-2 Mpro-IN-5 |
Purity | 98.00% |
MW | 638.73 |
SMILES | CCOC(=O)/C=C/[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@@H](CC3=CC=C(C=C3)F)NC(=O)OC(C)(C)C |
Formula | C34H43FN4O7 |
Biological Activity | SARS-CoV-2 Mpro-IN-5 is a dual inhibitor targeting Main Protease (M Pro) and Cathepsin L (CatL) with IC50 values of 1800 nM and 145 nM, respectively. This compound demonstrates antiviral activity by inhibiting SARS-CoV-2 replication in hACE2 expressing A549 cells, with an IC50 value of 14.7 nM. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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